Harms then came up with the double-helix hat stand.
Klijn did his PhD work at both the Netherlands Cancer Institute in Amsterdam (four days a week) and at TU Delft. His mission was to find cancer-causing genes in biological samples. Klijn used recent biological technologies, which enable reconstruction of the processes that led to cancer.
Klijn: “The central question was: who dunnit? That’s a typical question for the 1920-1930’s detective stories. Like them, I had many suspects: genes that had been affected. But which genes were the cause and which the casualties? Finally, we did find some highly suspect genes, which will be tested in living cells. Another finding came as a surprise: some genes only cause trouble in combination with others. Actually, these conspiracies appear to be very important.”
Christiaan Klijn, ’Who dunnit?, Finding Cancer Genes in Copy Number Data and Insertional Mutagenesis Data’, 9 Sept. 2011, Promotor: Prof. Marcel Reinders
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